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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3d5758c17339ef4a7d42c5ab25717bdc770b3e20d218a5e14947b9c68ae4050' 
  AND token = 'Utk74kDGT9pOatFpIKb3jzTfs5tvMrm/CSv5E6MyHkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}