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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb9aba602abca394884ef8f21c79ac51b0236b94fe4e85612de648028308d3a2' 
  AND token = 'j+OxOKgdQt/nr7UkaKw5ruzb4QfRbrjYcEAnh6mRc1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}