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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755b0593c85c604d2db970bb30e951d71977327b1a84975b50172c02fa21b390' 
  AND token = '7Vvpps0AHKOzMt9zLnb3RYg2IyK9prtHtF6KBHOf8Fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}