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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bdd9c9e33febe974be9179e9fb983965505d372cb37da323ca4cf67f3955c77' 
  AND token = 'CSlotFRar/VzoTi+EdCEfmWPUAazEWYKA6glpqw120s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}