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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec82ed4e75d1a36db0feb8af5b1f390d9a55f78c8e9029119e8a40070f2bc9ca' 
  AND token = 'TxMW+rP+5lwL/xYPoiqL3gfAwAqhkyH0lDjbG5P8fyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}