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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de332e3f7c492e0f1d4affec96176b41c75a335b6431d95f3fbfe679ce806270' 
  AND token = 'wneS13nHiPxQUbQ0rGS2FnQ43hlD8ao/uymYeP5hgBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}