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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20103d49a907ad74518082dff8eb39b42e4ac0075a7f1f25d4aaf4451960f4a5' 
  AND token = 'bxXQa0ymEWgzCaRlWwnqkyuDCbClh/l0okQLqgvH5CY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}