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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7180412158de19fd9fc66da171f5172fb4c799a0fb6d2afde65e16105689ed6b' 
  AND token = '2pwmYUqNaCnEnft9y7rH8ggOpVqB0VqgvCL9A8PROX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}