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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2c1ec9900bb23eadad5b87a01e0448e3954e6e29e1c7b187102058640eb2584' 
  AND token = 'UW/oOQcHe346UfwmobbFQ8vcbDQmMRP0O9Ia/ebZUn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}