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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e6b6a46e173fc308903089a947f62d0b38c7e4ee2a15c9ca5c8c5cde7b975f' 
  AND token = 'GF0V+uQAUi1ik48K72OkGPr8ZQJTqMrXO83PGe/EKIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}