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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fbb793ab81bccd18bdf6153cd35a0c05564fbc7f7b3dad3e17a99bd5c1a1650' 
  AND token = 'Sa6wOB+AfQt89+IGFMH+tz12YvFHA305o7BVz7tj2M4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}