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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28d01f53b03c610501bde087cc5ed6df653055a28afa5fca20ec4b32bce25a9b' 
  AND token = 'ICfxGo7PppVyz917FSL7YdqbsqmgTMNbMywm59Z0YSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}