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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6f1ce11a28aeb73941542a0653ad6581f65d3c708df1ef47dcde1c6ca12e2f0' 
  AND token = 'sNj1Jiw09rfJavr0BJO2I3pXWaRx8JXrnIH0jsw0vFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}