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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fb20482c0a110bb617c6511f07d8be6e44b22e5f4992a6ee1065003a01c3e62' 
  AND token = 'zENPnQ2DuJbzGnRkWs+ybFpQWCgNbYL5++Rn3wiSZwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}