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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a3bdf5a3e803aafa3e481c5c80fbd88d4fdc4811e29c5d29631265418b3a418' 
  AND token = 'LidSm0UV+HfLjSCD7rTkxmag76NXtTOxGPZ6SnMWh0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}