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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c487526bda124a11367f25a1ea9dfd0b4c1c741e3c50d5ca943dddaa2dc287' 
  AND token = 'fHqh4Jx4BlYkCYrQjHaKKWjd43s3+EePBNVTypdppeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}