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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81a4785e63d9f52cfc20eeb44449b8cdafe6414a305f4c571f6485b18b3853bb' 
  AND token = 'BBRtKBR0qRsoR8FsJ84EG3F0UBHoObIW5QXpFbXC0Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}