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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6a193ffc512642c3c8213d159147a58c53ec1fb675e22d7bc595d55454b4a48' 
  AND token = 'S3OPE5gO9yOiJb4U9pIXq2VCaevo/hkeNo34lVx5bIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}