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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f2dc6f7b736709d55ccf689868f1aa9d906e65739d38fb4f04d9406fb52dc6e' 
  AND token = 'FRcjWCIf4mdSYNzLxEJUBHP8SLJcd9+XuEF6h5wnTJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}