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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d96f6dc1b7254ebeb3765cb088b907ea9d19ffe65f5f28d9cf44a4206e5b0d2' 
  AND token = '54gA2cRmqtb+KtWZHki2xgUWLtKyKtaXZxcYjowkMKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}