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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac1765d1aba3df125e8362dedae128951a075b6f37d2bc528875da8bac90cb1' 
  AND token = 'M+hcFB7UX51vJX7ZYN79NrnPc3g+rfPczTcef2r0Xe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}