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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543b2cda175c9186181dd192bd06510e8022555082c182531f2498657e9fa12e' 
  AND token = 'XGTiECZYolHT4G/3zlcHzyZ2191x1iZKbEu/W3cE8Ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}