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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f06ff57ea76068ced2ff92ef75439ec7b9e8bbe7d05ce0206be7513d731e4973' 
  AND token = 'ie5hvpeJ/3aTvNS00P7yXc4WSBHzWKaw45vp+EJKQAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}