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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df8102c9d4ec444b85661fe102a7aebed4ff2ae5b6657093bbed0fd1ccbc489f' 
  AND token = 'ppTEGWB67ToiX5LyAICcuvxdepf5B2PayPQj2V+ZI1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}