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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18134535f9cf4c3f0a8c75b461d54ce5e88d09a72489d061621108a61ea148e' 
  AND token = 'gbsdfEIw1LAKrk0xQlg7wCzTtjuRCHyW2BRClFpsm9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}