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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b3c3ef17ab1f49f282e75b294807f7c8fa3a80be6eb70c6df070701ecfdc262' 
  AND token = 'k/YVKpw0TuOsUZLHkFmS3c9sxu3JKtksTUH3aOujCqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}