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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64eb5520437392032cdc3cf61a1811938a6fab705d270a64490d097f1acdcd48' 
  AND token = 'rbFcFwv5e43f72zWg76f20/BT9Q+OP0aQs+lAfw5kEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}