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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ed45b58f6edb7a24449940a80f344a2b88eef1c71a5440aba4d6c60a1c06cd' 
  AND token = '0jsJ26JjiGGX8EZUCGz7xtc2Kl3frrWXcHW3oKRGqi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}