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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce1a53a1d818e66b671ad2fde4b37831735e15bacc8fd41452e09a2b15d850ea' 
  AND token = 'NJR144kMHYxCmJqWUvOWl2rjdk0jPESAunvrExFp+LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}