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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c41e2e1cbcd0040698d09a1b395c88ab9de81fc3332a8a7949f32d287c19d75' 
  AND token = 'ahYIgVX/haV1oxMoUvzDmfaH5t+w7dvbNgAnXDni5gY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}