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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8c1f3990beb3699991a22c528d43dcb54ee844c5008496874694ded9a9949e' 
  AND token = '1G79wucko0E6nrSmNoQ8HAjJBzj7FTiZkHImTLq1ubI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}