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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c8d435d0b36a0493400cc2b82aea26982ef3693b5bae5234035091adc34f2c2' 
  AND token = 'w27xVoPty5ptWddXrQKt458FKqxY/frgQMVkt/Tjbcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}