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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e227bc238cc67c9820c1473bcf79b6447c9c09eee0faf0f45c5edb56e91b17a6' 
  AND token = 'MNRvWherWyiQcPBjD7hsCFxHQyYNi9zQ3mk8J7b5UPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}