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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f1423a380fc75e371de2f76d7a0caa027a9dc34377648db497c06179c67849' 
  AND token = 'T0Bd2464wg8pACjNSm0QcCQi4Effs9u5Ga83X/KdOho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}