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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ff82ef6754fd0ea72c015de1a1e3468c1459077a02bf4c1b5170ced2d53123a' 
  AND token = 'fY/Br5SJMXRKtQNMAII3mEtPejavyyLpK2OdRy6Tqr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}