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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf25ba30f299e71dcea36ed70e882c3939797cea7cbb3a4460e0bda29f8fc946' 
  AND token = '9Rm/5EHoyLMV0SmF4Z/q7MFvgtdZ3TGU9a+fAckjnOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}