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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '285f394ad0133026d7d306a220f4438ca948c98c8391196e6b54cbda5c774720' 
  AND token = 'XSRMIqK39spNkkXeG0d5xQlwdhHqH8hhHeSj/vLtL1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}