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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f1905c8a1f4b7de85f152391900bbf43c94efd1aeaac1ff3534a57e7857eba' 
  AND token = 'zDmxXFVjFC3+8fNNfvxDMoEwLtBzuXkjPkdL+6KA4kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}