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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f46a2988da8e4a6a205cdf4bc736f7d65f01091e2402c50ada12864e99977a3b' 
  AND token = 'nPLG30pHcJWgyvdK0V6R4xezuB5snGJbxIC8q3gnMis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}