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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74a082dc39f936d8ad2c86985a05c8cfb89d6f7186be8c34a4dc29dacb02378b' 
  AND token = 'NrPqBUInjFikxKuLXaN4PW7TqYpMrX+o7oR5GDm2h1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}