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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7260c98ab8ac30931b74a38758a1d8a7be4111e9ae844bb1114e16e3c78c1c83' 
  AND token = 'afoeXm3dMpnUIlYdyGVpVrSEecw+gyVsRboevjnmxKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}