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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd18b386bf7341e5dc59a1c6a07f0e9671de5b459bbfd0849f627d507bfd3ce6' 
  AND token = '/Pu1IJmFZn7CKxbev2Rs12w9cD2AY5NvWbcOjuoeXvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}