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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '835db7fe37be07fafe8d06da9e38b072a81b557a43e62faa700838a10ba95c70' 
  AND token = 'V8+z+9YV4JfmoYufx7e+I4B1dS2JrDcfzbeegjaHa5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}