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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a222a62723e15212e2ee99c4b1380fcf41c1f984b68603c7f1e439399dc111a' 
  AND token = 'uYCERsdl8+3VS7mXVSxonEvvjIralPmcIk5+YAq8+3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}