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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '162a9d564f738997b68db4b9119a3c2b120822a43585b11d7340e2adcb168a05' 
  AND token = 'XgcLtjd3SWRhGH1wHOPikdX/IR64j0fag/uoFB0Kk54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}