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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '501bf0c37e46543d5c9bcf6440d310b55d79b1df0cfe29f58c066f263e69976b' 
  AND token = 'LLlDpNSbKNyCDwECDtQw23KPREWDe9xjDgaUXVGxw5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}