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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b178166d82e953711f621275f053a76fcb2654755915f8a03aaaf56f8f77be5c' 
  AND token = 'X64RCTGrqqZt8Cjvg2TOqkvOtfGABcVIxbE9UNZOMZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}