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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bca53fd54298f4349099e87f8dae9ff3045fdc227a9cda9bc35923fd80361e1' 
  AND token = '2oCiJSPexPuqMrBBTcEE8iU+Bgr3TmE3eEiegcSwIKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}