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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d8bf70a5992bd3b8ab8007bcd4028369e70c3104067cf0069489864284e0c21' 
  AND token = 'VP2svUgc+aEplT8b0nkkMU5Kj8q40U8iKAARL7vngJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}