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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b9282f4ed61260a09e4ceffb18b3b615945a279fc44d1193d70df3e9cf2923' 
  AND token = 'RuY7jPmQP1DMMROD24Ym5C1PeZTyr7ujRK8NstAlTic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}